
Characteristic changes in astrocyte properties during astrocyte-to-neuron conversion induced by NeuroD1/Ascl1/Dlx2
Brief intro:
- Author: Qing He, Zhen Wang, Yuchen Wang, Mengjie Zhu, Zhile Liang, Kanghong Zhang, Yuge Xu, Gong Chen
- Journal: Neural Regeneration Research
- Doi: https://www.doi.org/10.4103/NRR.NRR-D-23-01897
- Publication Date: 2025-06-01
Abstract
Quotation shows PackGene:AAV GFAP::GFP and AAV GFAP::NTF-P2A-GFP were packaged with the serotype 9 capsid (PackGene Biotech).
Research Field:Central nervous system
AAV Serotype:AAV9
Targeted organ:brain
Animal or cell line strain:mice
About PackGene
PackGene Biotech is a world-leading CRO and CDMO, excelling in AAV vectors, mRNA, plasmid DNA, and lentiviral vector solutions. Our comprehensive offerings span from vector design and construction to AAV, lentivirus, and mRNA services. With a sharp focus on early-stage drug discovery, preclinical development, and cell and gene therapy trials, we deliver cost-effective, dependable, and scalable production solutions. Leveraging our groundbreaking π-alpha 293 AAV high-yield platform, we amplify AAV production by up to 10-fold, yielding up to 1e+17vg per batch to meet diverse commercial and clinical project needs. Moreover, our tailored mRNA and LNP products and services cater to every stage of drug and vaccine development, from research to GMP production, providing a seamless, end-to-end solution.
